Aims
The Subcommittee on Drug Discovery and Development’s mission is to facilitate the use, understanding, public awareness, and application of medicinal chemistry and aspects of drug discovery and development internationally and world wide. Medicinal Chemistry is a major scientific discipline in the Subcommittee, and which is vitally important to the pharmaceutical industry. Medicinal chemists are actively involved in new drug discovery and in solving problems of designing molecules to optimize their biological properties.
Description
The Subcommittee generally meets twice yearly and provides an excellent forum for discussing projects through the exchange of information, views and ideas among chemists in Drug Discovery and Development from different countries, representing both academia and the pharmaceutical industry.
Since 2006, the Subcommittee organizes the IUPAC-Richter Prize in Medicinal Chemistry. In 2020, the most recent prize was awarded to John Macor (see release). Previous IUPAC-Richter Prizes were awarded to Malcolm F.G. Stevens in 2006, Jan Heeres in 2008, Arun K. Ghosh in 2010, Stephen Hanessian in 2012, Helmut Buschmann in 2014, Michael Sofia in 2016, and Peter D.J. Grootenhuis in 2018. See 2022 Call for Nominations.
Meeting Minutes
- Telecon Dec 2021 (pdf file – 72KB)
- Telecon Oct 2020 (pdf file – 77KB)
- Telecon Dec 2019 (pdf file – 102KB)
- Paris, France, 06 Nov 2019 (pdf file – 259KB)
- Telecon Mar 2019 (pdf file – 143KB)
- Telecon Oct 2018 (pdf file – 142KB)
- Tennessee, USA, 28 April 2018 (pdf file – 93KB)
- Vienna, Austria, 26 Aug 2017 (pdf file – 283KB)
- San Francisco, CA, USA, 1 Apr 2017 (pdf file – 370KB)
- Manchester, UK, 27 Aug 2016 (pdf file – 49KB)
- San Diego, CA, USA, 12 Mar 2016 (pdf file – 190KB)
- Antwerp, Belgium, 13 Sep 2015 (pdf file – 290KB)
- *Rio de Janeiro, Brazil, 27 Jan 2015 (pdf file – 461KB)
- Lisbon, Portugal, 6 Sep 2014 (pdf file – 302KB)
- Brussels, Belgium, 28 May 2014 (pdf file – 26KB)
- Dallas, TX, USA, 19-20 Mar 2014 (pdf file – 141KB)
- Istanbul, Turkey, 11 Aug 2013 (pdf file – 186KB)
- New Orleans, LA, USA, 6 Apr 2013 (pdf file – 233KB)
- Berlin, Germany, 1 Sep 2012 (pdf file – 80KB)
- San Diego, CA, USA, 29 Mar 2012 (pdf file – 233KB)
- Anaheim, CA, USA, 31 Mar – 1 Apr 2011 (pdf file – 179KB)
- Brussels, Belgium, 3-4 Sep 2010 (pdf file – 25KB) and summary report (pdf file – 74KB)
- San Francisco, CA, 20-21 Mar 2010 (pdf file – 143KB)
Activity Reports
In recent years, the Subcommittee has published several books, produced important glossaries on terms for use in medicinal chemistry, pharmaceutics, biomolecular screening, and computational drug design, and released various articles. It has also organized educational schools in medicinal chemistry, especially in Latin America and India. (An overview of the accomplishments during the last decade has been published in Chem. Int. Sep 2015, pp. 17-20; DOI: 10.1515/ci-2015-0506)
The output of these activities are readily accessible via the following project pages:
(each project page includes details on the original project setting and links to outcomes and/or publications)
Books
- Successful Drug Discovery, Volume-5 (2021) [project 2019-021-1-700]
DOI: 10.1002/9783527826872 (Wiley Online Library) - Successful Drug Discovery, Volume-4 (2019)
DOI: 10.1002/9783527814695 (Wiley Online Library) - Successful Drug Discovery, Volume-3 (2018)
DOI: 10.1002/9783527808694 (Wiley Online Library) - Successful Drug Discovery, Volume-2 (2016)
DOI: 10.1002/9783527800315 (Wiley Online Library) - Successful Drug Discovery (2015)
DOI: 10.1002/9783527678433 (Wiley Online Library) - Analogue-based Drug Discovery III (2012)
DOI: 10.1002/9783527651085 (Wiley Online Library) - Analogue-based Drug Discovery II (2010)
DOI: 10.1002/9783527630035 (Wiley Online Library) - Analogue-based Drug Discovery (2006)
DOI: 10.1002/3527608001 (Wiley Online Library)
Glossaries
- 2010-057-3-700: Glossary of Terms used in Computational Drug Design
or link to 2015 IUPAC Recommendations - 2008-010-1-700: Glossary of Terms used in Medicinal Chemistry
or link to 2013 IUPAC Recommendations - 2004-019-3-700: Glossary of Terms used in Biomolecular Screening
or link to 2011 IUPAC Recommendations - 2003-044-1-700: Glossary of Terms used in Combinatorial Chemistry
- 2001-049-2-700: Glossary of Terms Related to Pharmaceutics
or link to 2009 IUPAC Recommendations - 2000-009-1-700: Glossary of Drug Metabolism Terms
or link to 2021 IUPAC Technical Report
Training and Development
- 2014-022-1-700: Highlights in Medicinal Chemistry — Short Course to Postgraduate, University of Rio de Janeiro (UFRJ)
- 2014-011-2-700: Medicinal Chemistry in Drug Discovery, India
- 2009-033-1-700: New Drugs for Neglected Tropical Diseases — Survey of Research in Latin America
- 2004-028-1-700: Practical Studies for Medicinal Chemistry — Online Resource