Chemistry and Human Health Division

Aims

Division VII group photo at the 50th IUPAC General Assembly in Paris
Division VII having fun with post-it notes and prediction of future…
Division VII members in Palais des Congres in Paris

Description

The mission of Division VII is to promote pure and applied chemistry in the service of human health and well-being. Major aspects are the development of therapeutic drugs, the standardization of clinical laboratory methods and the protection of humans from potential harmful substances. All three sectors have seen many new developments in the past 20 years, and Division VII helps IUPAC and the chemical community to keep up with the rapid changes in the health-related areas.

Terms of Reference

IUPAC Richter Prize 2020 awarded to John Macor for the discovery of eletriptan and rimegepant used in the treatment of migraine

John Macor, PhD is Awarded the 2020 IUPAC-Richter Prize

The 2020 IUPAC-Richter Prize in Medicinal Chemistry has been awarded to John Macor, PhD, Global Head Integrated Drug Discovery, Sanofi

Dr. Macor received the award in recognition of his outstanding creative contributions in the field of medicinal chemistry research on drugs for the treatment of migraine. John’s improvements to the triptan core structure fueled the discovery of Eletriptan (Relpax®), an effective drug within the class that displayed superior pharmacokinetics compared to the flagship triptan drug at that time, sumatriptan. John Macor is a co-discoverer of two advanced clinical candidates within a new class of small-molecule anti-migraine drugs, the calcitonin gene-related peptide (CGRP) inhibitors. One of these, Rimegepant, is currently under approval review by the FDA. John Macor’s contributions to drug design and consistent support  of medicinal chemistry have earned him this prestigious prize.

The IUPAC-Richter Prize, comprising a plaque and a check for USD 10,000, will be presented at the XXVI EFMC-ISMC International Symposium on Medicinal Chemistry to be held in Basel, Switzerland (September 6 – 10). The plaque will be signed by Professor Christopher M.A. Brett, President of IUPAC, Gábor Orbán, Chief Executive Officer of Gedeon Richter Plc (Budapest, Hungary), and Professor János Fischer, Chair of the IUPAC-Richter Prize selection committee. John Macor will present an acceptance lecture at this Symposium and a second lecture at the 37th ACS National Medicinal Chemistry Symposium to be held in New York (June 28-July 1).

The Chair of the current international Selection Committee is Dr. Janos Fischer (IUPAC). The jury members are Dr. Yves Auberson (Switzerland), Dr. Jonathan Baell (Australia), Dr. Helmut Buschmann (Germany), Dr. Wayne Childers (USA), Dr. Kazumi Kondo (Japan), Dr. David Rotella (USA), Dr. Gerd Schnorrenberg (Germany), Dr. Mike Waring (UK)  and Dr. Patrick Woster (USA).  The Chair coordinates the work of the Selection Committee and the members of the Selection Committee cast their vote for their choice of awardee.

The IUPAC-RICHTER Prize is recognized internationally, as demonstrated by a high number of nominations of successful and internationally renowned scientists in drug research. The process of deciding who among the many deserving nominees receives the award is always difficult. The history of 

 

 

Subcommittees and Commissions

Meeting Minutes

Activity Reports

  • Report 2019, by Prof. Rita Cornelis (pdf 92KB)
  • Report 2018, by Prof. Rita Cornelis (pdf 88KB)
  • Report 2016 (prepared for Bureau in Montreal) by Dr. Tom Perun (pdf 94 KB)
  • Report 2014-2015 (prepared for Council in Busan) by Dr. Tom Perun (pdf 91 KB)
  • Report 2013, by Prof. D.M. Templeton (pdf 136 KB)
  • Report 2012, by Prof. D.M. Templeton (pdf 237 KB)
  • Report 2011, by Prof. D.M. Templeton (pdf 183 KB)
  • Report 2010-2011, by Prof. D.M. Templeton (pdf 255 KB)
  • Report 2010, by Prof. D.M. Templeton (pdf 226 KB)

Publications:  

Gerhardt, P., “Medicinal Chemistry in the New Millenium,” Chemistry International, Vol. 24, No. 5, p. 4, September 2002 (PDF)
Ganellin, R., “Accomplishments During the Past Decade and Relationships with Industry,” Chemistry International, Vol. 24, No. 5, p. 8, September 2002 (PDF)
Gerhardt, P., “On the Reality of Virtual Libraries,” Chemistry International, Vol. 24, No. 4, p. 16, July 2002 (PDF)

An Ontology on Property – For Physical, Chemical and Biological Systems, by Dr René Dybkær (2004)

Links to related Organizations:

Emeritus Fellows