To provide standardized definitions of terms and technologies used in biomolecular screening supporting drug discovery.
Over the past 15 years, high throughput screening (HTS) of small molecules has become a mainstay in the drug discovery process both in lead discovery and lead optimization. In both HTS and routine screening to optimize lead structures, new technologies, techniques and terminology have emerged. A definitive glossary of biomolecular screening terms will be broadly useful to scientists involved in the drug discovery process. The glossary will be generated in collaboration with the Society for Biomolecular Screening.
May 2009 – A manuscript is being prepared for publication in Pure Appl. Chem. A final document is submitted to public review comments until 30 September 2009. (> provisional recommendations at ../provisional/abstract09/proudfoot_300909.html)
Feb 2011 - project completed – IUPAC recommendations titled Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)’ published in Pure Appl. Chem. 2011, Vol. 83, No. 5, pp. 1129-1158 doi:10.1351/PAC-REC-09-05-03
page last modified 21 Feb 2011