Project Details Solubility data related to industrial processes. Acetonitrile: ternary and other multicomponent systems

Project No.:
Start Date:
01 January 2003
End Date:
17 October 2007
Division Name:
Analytical Chemistry Division
Division No.:


Series: Solubility Data Series; editor-in-chief: Mark Salomon

This project will exhaustively compile and critically evaluate published solubility data for ternary and higher systems of acetonitrile with all other components. The results of this work will be prepared in the standard format of the IUPAC-NIST Solubility Data Series for publication in the Journal of Physical and Chemical Reference Data and for inclusion in a web-accessible database being prepared by the US National Institute of Standards and Technology (NIST).


The IUPAC Solubility Data Project (SDP) compiles and critically evaluates data on chemical solubility and disseminates the resulting information to the widest possible range of users by traditional (printed on paper) and electronic (web-accessible database) means. Under the direction of the Subcommittee on Solubility and Equilibrium Data (SSED) of the Analytical Chemistry Division, the SDP has focused on five subject areas of wide importance.

The systems to be covered by this project fit into one of these priority areas, Solubility Related to Industrial Processes. Acetonitrile is one of the best extractive distillation solvents for separation of close boiling paraffinic and olefinic hydrocarbons (hydrocarbons C5 +- acetonitrile +- water: isoprene +- acetonitrile +- water, trimethylethene +- acetonitrile +- water, isopentane +- acetonitrile +- water) and for the separation of paraffinic and aromatic hydrocarbons (hexane +- benzene +- acetonitrile +- water).

Others nitriles are used for separation of 1-alcohols, for example, water +- benzonitrile +- ethanol (1-propanol, 2-propanol, 1-butanol).

As the chemical process industry seeks more efficient and less energy-intensive separation techniques, liquid-liquid extraction based on selective solubilities are becoming more common.


1st part: “Acetonitrile Binary Systems,” SDS Volume 78, V.P. Sazonov, et. al. J. Phys. Chem. Ref. Data, 2002, 31, No. 4, 989-1133.
> View abstract

Part 2. “Acetonitrile: Ternary and Quaternary Systems,” and Part 3. “C-3 and Higher Nitriles: Binary and Multicomponent Systems” will also be published as part of the IUPAC-NIST Solubility Data Series. in J. Phys. Chem. Ref. Data. 2007, 36, No. 3, 733-1131 > View abstract

Part 3. “C-3 and Higher Nitriles: Binary and Multicomponent Systems” > see project 2007-047-1-500

282 compilations and 35 critical Evaluations have already been reviewed within the Task Group; estimated to be completed during 2006.
> Nov 2004 report update (pdf file – 12KB)

> May 2006 report update (pdf file – 11KB)

> View SDS published Volumes

Project completed